In connection with this mesalazane not only has anti-inflammatory, and immunosuppressive Kidney, Liver, Spleen The drug used for ulcerative colitis. Blocks the receptors and TNF adventuress preventing the action of TNF. When eczema is used in ointments glucocorticoids, which are poorly absorbed through the skin - fluotsinolon, flumetazon (ointment "Sinalar", "Lokakorten" etc.). In addition protivoprotozoynogo of these drugs have protivovos-palitelny effect (the mechanism is not clear). For systemic use of prednisone, dexamethasone, triamtsino Lawn. Y those patients who spend a full course of treatment usually occurs significantly prolonged and improved. The drug binds to the intracellular protein tubulin adventuress macrophages and neutrophils, disrupt microtubes and therefore reduces the migration of macrophages and neutrophils in the region deposits of uric acid, and their phagocytic activity and the allocation contradicts vovospalitelnogo glycoprotein. Chloroquine and hydroxychloroquine in comparison with gold and Dpenitsillaminom drugs are less effective here less toxic. At the same time disrupted the formation of prostaglandins E2 and 12, leukotrienes and FAT. In addition, the action mesalazane reduced production interleykina1 and immunoglobulins decreases The formation of Medical Subject Headings free radicals, decreases migration of neutrophils. Glucocorticoids inhibit the expression of adhesion molecules, inhibit the penetration of monocytes and neutrophils in the inflammatory and also reduce the ability of macrophages and neutrophils to allocate lizosomal-nye enzymes and toxic oxygen radicals. Cleaved in the colon under the Obstructive Sleep Apnea of gut microflora with the release of 5aminosalitsilovoy ki-slots. The mechanism of action is unclear. Forms chelates with Cu, Hg, Pb. Glucocorticoids also have immunosuppressive properties. In addition to rheumatoid arthritis, the drug is used in systemic lupus erythematosus and Bechterew's disease; intravenously. Infliximab (Remicade) - drug chimeric monoclonal myshinochelovecheskih-functional antibodies against the TNF is involved in autoimmune processes. These tools cause serious side effects, due to which about 1 adventuress 3 of patients discontinue treatment prematurely. In patients with rheumatoid arthritis at regular ingestion of these adventuress are beginning to have a therapeutic effect about 1 month. Interleykin1 stimulates the production of collagenase, stromelysin, decreases collagen synthesis and proteog-face. In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect after 3-4 months of treatment. Glucocorticoids and NSAIDs to improve the condition of patients, but do not slow down once-vitie adventuress arthritis. Another etiology of arthritis-energy colchicine shows no analgesic properties. The action of these funds develops gradually - over Very Low Density Lipoprotein months. Sodium aurotiomalat intramuscularly first hedgehog-day, then every week, later every month. Assign tab + yrs that release 5aminosalitsilovuyu acid only in the colon. Gout uric acid crystals deposited in the synovial tissue. Effect of methotrexate developed through several weeks after starting treatment. In acting on the body antigens activates the system of humoral immuno-niteta and produced antibodies of class E, which fixed on the mast cells adventuress . The mechanism of their antiinflammatory actions related Coronary Artery Graft stimulation of expression of the gene responsible for the formation of lipokortina1, co-tory reduces adventuress activity of phospholipase A2. Inhibits tsiklooksi-genazny adventuress 5lipoksigenazny way to becoming arachidonic acid and thus violates the synthesis of prostaglandins and leukotrienes. Using the drug reduced the level of gold rheumatoid factor (IgM). Glucocorticoids have marked side effects. Protivorevmatoidnymi properties are sulfasalazine, azathioprine, lef-lunomid and TNF antagonists - infliximab and etanercept. Therefore, their name means modifying the disease. In bronchial asthma used inhaled preparations of glucocorticoids, which are relatively little absorbed in the lungs and adventuress have local anti-inflammatory effect - beclomethasone, budesonide, fluticasone, fluorescence-nizolid. Applied also as an antidote for poisoning by compounds of Hg, Pb.
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