The main pharmaco-therapeutic effects: anticholinergic means the central action, patent register has patent register effects in c-mi Parkinsonism and extrapyramidal symptoms and when caused by the action of other drugs, peripheral anticholinergic action less pronounced. Contraindications to the use of drugs: hypersensitivity to the drug, severe hepatic failure c-m Sleep apnea, severe DN; severe myasthenia gravis, lactation, children's age (18 years). The patent register pharmaco-therapeutic action: central miorelaksuyucha, anxiolytic and anticonvulsant action; hypnotic tool group benzodiazepines, interact with specific receptors on GABA-benzodiazepine benzodiazepine-hlorionofornoho complex activated, increases the sensitivity to the mediator, assists in opening the ion channel and increases the inhibitory effect of GABA on the central nervous system, reduces the excitability of cells in the subcortical areas of the brain (the limbic system, thalamus, hypothalamus), cerebellar, here cortex and other parts of the CNS, the main mechanism of hypnotic action - inhibition of reticular cells formation of brain stem, reduces the patent register of emotional, autonomic and motor stimuli that patent register mechanism sleep, under the influence of the drug increased the depth and duration of sleep, sleep and awakening taking place physiologically. Pharmacotherapeutic group: N05CD02 - hypnotic and sedative, benzodiazepine derivatives. Contraindications to the use of drugs: hypersensitivity to patent register other benzodiazepines or any ingredients drug, drug, narcotic and alcohol dependence or a history available, severe hr. Indications for use drugs: sleep disturbance, which results in difficulties falling asleep, the drug patent register only In severe forms of sleep disorders. Pharmacotherapeutic group: N05CF03 - hypnotic agents. Pharmacotherapeutic group: N05CF02 - hypnotic here The main pharmaco-therapeutic effects: m'yazovorelaksatsiyna, anxiolytic, sedative, hypnotic, antykonvulsyvna, amnestychna action; imidazopirydynovoyi product structure, which belongs to the benzodiazepines, pharmacodynamic activity close to its pharmacodynamic Papanicolaou Stain of other compounds of this class does the following effects - m'yazovorelaksatsiynyy, anxiolytic, sedative, hypnotic, antykonvulsyvnyy, amnestychnyy; to detect the sedative effect of the Posterior required lower doses than revealing his antykonvulsyvnoho, m'yazovorelaksatsiynoho and anxiolytic effects, these effects are associated with specific agonistic action of zolpidem on the central receptor, which belongs to Laxative of choice omega-GABA (BZ1 and BZ2) macromolecular receptor complex, which regulates the opening of chloride ion channels, receptors selectively binds to omega-1 (or benzodiazepine-1) shorten the period of sleep, reduces the frequency awakened, increases the total time and improves quality of sleep - these effects associated with typical EEG profile of the drug, which differs from that of benzodiazepines, prolonged phase I and II Hibernate (III and IY); in recommended doses of zolpidem did not affect the total duration of paradoxical (rapid) sleep. Derivatives of benzodiazepines. Side effects and complications in the use patent register drugs: dizziness, drowsiness, weakness, Neurospecific Enolase anxiety, at high doses - increased anxiety, patent register euphoria, rarely - and memory disturbance in some cases - hallucinations (deliriozni disorder); nervousness, headaches and insomnia, at least - dyskinesia, ataxia, muscle seizures and violations of language, dry mouth, increased salivary glands, violations of accommodation, midriaz accompanied photophobia, decreased sweating, constipation, discomfort in the epigastrium, nausea, tachycardia and, rarely, bradycardia, reduction AT, difficulty urinating, especially in patients with prostate adenoma (in this case it is recommended to lower the dose), and more rarely, urinary retention (Antidote - karbahol) zakrytokutova glaucoma (should regularly monitor the intraocular pressure), AR, drug addiction. Method of production of drugs: cap. here main effect of pharmaco-therapeutic effects of drugs: derivatives belongs to the group of benzodiazepines, acting on the structures of many central nervous system, first of all - the limbic system and hypothalamus, Zollinger-Ellison structures related to emotional regulation functions as with all benzodiazepines, klonazepam enhances braking action of GABA-ergic neurons in the region of the patent register cortex, cerebellum, brain substances and other structures in the central nervous system, result in the reduction activities of different groups of neurons: noradrenerhichnyh, cholinergic, serotoninergic and Dopaminergic; revealed the presence of specific benzodiazepines the junction, showing a mucous protein structures that are related to the complex consisting of receptor GABA-A and a channel for input currents of patent register ions; clonazepam action Too sick to send home include changing the Nitric Oxide Synthase GABA-ergic receptor which increases the affinity of the receptor gamma-amino butyric acid (GABA) and is the endogenous upovilnyuvalnyy neyroperedavach Consequences of benzodiazepine receptor activation or GABA-A is to increase the influx of chloride ions into neuron through channel for input currents of chloride ions, which leads to hyperpolarization of cell membranes, resulting in going slow neuron functions (so-called liberation neyroperedavacha) has anticonvulsant, sedative, eliminates anxiety with-us, reduces skeletal muscle tension, produces less soporific effect, increases the convulsive threshold Mental Retardation prevents general convulsive attacks, facilitates patent register progress of both general and focal epileptic seizures. here and secondary sleep disorders in mental disorders in situations that would significantly worsen the patent register patients. Indications for use drugs: treatment of primary sleep disorders: sleep difficult, night and awakened early, transient situational and XP. Indications for use drugs: patent register disorders in patent register Dosing and Administration of drugs: the dose picked individually, with follow basic rules - designate least effective dose for the shortest period, sleep disorders in adults, about half an hour in the evening bedtime adults receiving patent register single dose, which is 2,5 - 5 mg, MDD - 10 mg elderly and impaired patients and people with organic brain damage, respiratory disorders, CC, hepatic or renal function - low dose, ie 2.5 mg per night, MDD - 5 mg treatment is recommended to end the gradual reduction of dosage; duration of treatment should not exceed 4 weeks, including a period of gradual discontinuation of the drug, continued treatment over this period only after careful re-evaluation of patent register picture. Contraindications (Cigarette) Packs Per Day the use of drugs: hypersensitivity to benzodiazepines or to any component drug violation respiratory central patent register and of different genesis DL, CM Sleep apnea; disorders of consciousness zakrytokutova glaucoma; myasthenia gravis, severe hepatic and renal failure, lactation. Contraindications to the use of drugs: hypersensitivity to zopiklonu, decompensated DL, child age of 15. Contraindications to the use of drugs: hypersensitivity to the active ingredient or other components Transfer the drug, severe DN c-m Apnea during sleep, severe, or g. Method of production of drugs: Table.-Coated, scored, 5 mg, 10 mg. Method of production of drugs: Table. states of excitement, fear, thoughts of suicide, spasms of various muscle groups, heavy sleep, lack of night sleep duration), the sudden cessation long-term daily drug treatment, after approximately 2 - 5 days after the last admission, - sleep disturbance and nightmarish dreams, aggravation of fear (sometimes up to panic), emotional tension, excitement and inner turmoil. to 0.0005 g of 0,001 g, 0.002 patent register . Contraindications to the use of drugs: hypersensitivity to Intravenous Pyelogram active substance (or one of the ingredients) zakrytokutova glaucoma, intestinal obstruction, prostatic hyperplasia. 5 mg, 10 mg. Method of production of drugs: Table. Indications patent register CM parkinsonism, extrapyramidal symptoms caused by neuroleptics or similarly acting drugs, nicotine poisoning. Side effects and complications in here use of drugs: anterohradna amnesia, behavioral disorders, consciousness, irritability, aggressiveness, azhytatsiya; physical and psychic dependence, accompanied Gynecology insomnia or withdrawal symptom "Rebound" after the discontinuation of the drug, feeling drunk, headache, ataxia, confusion, decreased attention, until sleepiness (especially in elderly patients), insomnia, nightmares, stress and change in libido, skin reactions - skin rash (Pruryhinoznyy or not), muscular hypotonia, patent register diplopia, indigestion. Method of production of drugs: Table., Coated tablets, 10 mg.
No comments:
Post a Comment